Reaction Details Report a problem with these data
Target
Muscarinic acetylcholine receptor
Ligand
BDBM50010101
Substrate
n/a
Ki
1.51±n/a nM
Comments
PDSP_3900
Citation
 Lazareno, S; Buckley, NJ; Roberts, FF Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells. Mol Pharmacol 38:805-15 (1990) [PubMed] 
Target
Name:
Muscarinic acetylcholine receptor
Synonyms:
CHRM4 | Cholinergic, muscarinic M4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
53017.26
Organism:
RABBIT
Description:
Cholinergic, muscarinic M4 CHRM4 RABBIT::PPPPPP
Residue:
478
Sequence:
MANFTPVNGSSSNQSVRLVTSAHNRYETVEMVFIATVTGSLSLVTVVGNVLVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGQKEKKAKTLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPMADKDTSNESSSGSATQNTKERPATELSTAEATTPAMSAPPLQPRTLNPASKWSKIQIVTKQTGNECVTAIEIVPATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR
  
Inhibitor
Name:
BDBM50010101
Synonyms:
2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate | Bentyl | Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl ester | CHEMBL1123 | DICYCLOMINE | Dicycloverin
Type:
Small organic molecule
Emp. Form.:
C19H35NO2
Mol. Mass.:
309.4867
SMILES:
CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1
Structure:
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