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Target
Cholecystokinin
Ligand
BDBM82384
Substrate
n/a
Ki
3500±n/a nM
Comments
PDSP_2275
Citation
 Evans, BE; Bock, MG; Rittle, KE; DiPardo, RM; Whitter, WL; Veber, DF; Anderson, PS; Freidinger, RM Design of potent, orally effective, nonpeptidal antagonists of the peptide hormone cholecystokinin. Proc Natl Acad Sci U S A 83:4918-22 (1986) [PubMed]  Article 
Target
Name:
Cholecystokinin
Synonyms:
CCKN_RAT | Cck
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12844.29
Organism:
RAT
Description:
Cholecystokinin 0 RAT::P01355
Residue:
115
Sequence:
MKCGVCLCVVMAVLAAGALAQPVVPVEAVDPMEQRAEEAPRRQLRAVLRPDSEPRARLGALLARYIQQVRKAPSGRMSVLKNLQGLDPSHRISDRDYMGWMDFGRRSAEDYEYPS
  
Inhibitor
Name:
BDBM82384
Synonyms:
Benzyloxycarbonyl CCK(27-32)NH2
Type:
Small organic molecule
Emp. Form.:
C43H53N7O13S3
Mol. Mass.:
972.115
SMILES:
CSCC[C@H](NC(=O)[C@@H](N)Cc1ccc(OS(O)(=O)=O)cc1)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)OCc1ccccc1
Structure:
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