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Target
5-hydroxytryptamine receptor 3A
Ligand
BDBM82474
Substrate
n/a
Ki
0.94±n/a nM
Comments
PDSP_3690
Citation
 Green, T; Stauffer, KA; Lummis, SC Expression of recombinant homo-oligomeric 5-hydroxytryptamine3 receptors provides new insights into their maturation and structure. J Biol Chem 270:6056-61 (1995) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 3A
Synonyms:
5-HT-3 | 5-HT3-A | 5-HT3A | 5-HT3A Serotonin Receptor | 5-HT3R | 5-hydroxytryptamine receptor 3 | 5-hydroxytryptamine receptor 3A | 5HT3A_MOUSE | 5ht3 | Htr3 | Htr3a | Serotonin 3 receptor (5HT3) | Serotonin 3a (5-HT3a) receptor | Serotonin receptor 3A | Serotonin-gated ion channel receptor
Type:
n/a
Mol. Mass.:
56056.00
Organism:
Mus musculus (house mouse)
Description:
5HT3A
Residue:
487
Sequence:
MRLCIPQVLLALFLSMLTAPGEGSRRRATQEDTTQPALLRLSDHLLANYKKGVRPVRDWRKPTTVSIDVIMYAILNVDEKNQVLTTYIWYRQYWTDEFLQWTPEDFDNVTKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYVHHRGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINITLWRSPEEVRSDKSIFINQGEWELLEVFPQFKEFSIDISNSYAEMKFYVIIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQRPVPDWLRHLVLDRIAWILCLGEQPMAHRPPATFQANKTDDCSGSDLLPAMGNHCSHVGGPQDLEKTPRGRGSPLPPPREASLAVRGLLQELSSIRHFLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWSIWHYS
  
Inhibitor
Name:
BDBM82474
Synonyms:
1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE | CAS_2113-05-5 | m-chloro-phenyl-biguanide
Type:
Small organic molecule
Emp. Form.:
C8H10ClN5
Mol. Mass.:
211.652
SMILES:
[#7]\[#6](-[#7])=[#7]\[#6](-[#7])=[#7]-c1cccc(Cl)c1 |w:6.6|
Structure:
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