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Target
Alpha-2A adrenergic receptor
Ligand
BDBM50030614
Substrate
n/a
Ki
54.5±n/a nM
Comments
PDSP_1717
Citation
 Bockman, CS; Jeffries, WB; Abel, PW Binding and functional characterization of alpha-2 adrenergic receptor subtypes on pig vascular endothelium. J Pharmacol Exp Ther 267:1126-33 (1993) [PubMed] 
Target
Name:
Alpha-2A adrenergic receptor
Synonyms:
Alpha-2A adrenergic receptor | adrenergic Alpha2 | adrenergic Alpha2A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48998.96
Organism:
PIG
Description:
adrenergic Alpha2 0 PIG::P18871
Residue:
450
Sequence:
MGSLQPEAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKAGGGGQQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAAAALPGGAERRPNGLGPERGVGRVGAEAEPLPVQLNGAPGEPAPAGPRDADGLDLEESSSSEHAERPPGPRRSERGPRAKSKARASQVKPGDSLPRRGPGAPGPGAPATGAGEERGGVAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPPTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
  
Inhibitor
Name:
BDBM50030614
Synonyms:
5-Chloro-8-methyl-1-vinyl-6,7,8,9-tetrahydro-2-thia-8-aza-benzo[cd]azulene | CHEMBL25467 | SK&F-104856 | SK-104856 | SKF 104856
Type:
Small organic molecule
Emp. Form.:
C14H14ClNS
Mol. Mass.:
263.786
SMILES:
CN1CCc2c(Cl)ccc3sc(C=C)c(C1)c23
Structure:
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