Reaction Details Report a problem with these data
Target
Cholecystokinin
Ligand
BDBM82514
Substrate
n/a
Ki
1.2±n/a nM
Comments
PDSP_2245
Citation
 Patel, S; Smith, AJ; Chapman, KL; Fletcher, AE; Kemp, JA; Marshall, GR; Hargreaves, RJ; Ryecroft, W; Iversen, LL; Iversen, SD Biological properties of the benzodiazepine amidine derivative L-740,093, a cholecystokinin-B/gastrin receptor antagonist with high affinity in vitro and high potency in vivo. Mol Pharmacol 46:943-8 (1994) [PubMed] 
Target
Name:
Cholecystokinin
Synonyms:
CCK | CCKN_PIG | Cholecystokinin B
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12528.64
Organism:
GUINEA PIG
Description:
Cholecystokinin B 0 GUINEA PIG::P01356
Residue:
114
Sequence:
MNGGLCLCVLMAVLAAGTLAQPVPPADSAVPGAQEEEAHRRQLRAVQKVDGESRAHLGALLARYIQQARKAPSGRVSMIKNLQSLDPSHRISDRDYMGWMDFGRRSAEEYEYTS
  
Inhibitor
Name:
BDBM82514
Synonyms:
1-[[(3R)-2,3-Dihydro-1-methyl-2-oxo-5-[(hexahydro-1H-azepin)-1-yl]-1H-1,4-benzodiazepin]-3-yl]-3-(3-methylphenyl)urea | CHEMBL543712 | L-737,415 | L-738416
Type:
Small organic molecule
Emp. Form.:
C24H29N5O2
Mol. Mass.:
419.5194
SMILES:
CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cccc(C)c2)C1=O)N1CCCCCC1 |c:9|
Structure:
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