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Target
Kappa-type opioid receptor
Ligand
BDBM82555
Substrate
n/a
Ki
11±n/a nM
Comments
PDSP_1281
Citation
 Raynor, K; Kong, H; Chen, Y; Yasuda, K; Yu, L; Bell, GI; Reisine, T Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors. Mol Pharmacol 45:330-4 (1994) [PubMed] 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM82555
Synonyms:
CAS_4424 | NSC_4424 | Naloxonazine
Type:
Small organic molecule
Emp. Form.:
C38H42N4O6
Mol. Mass.:
650.7633
SMILES:
Oc1ccc2CC3N(CC=C)CCC45C(Oc1c24)C(CCC35O)=NN=C1CCC2(O)C3Cc4ccc(O)c5OC1C2(CCN3CC=C)c45 |w:24.28,18.21,TLB:27:28:43.42.41:31.32.47,22:21:5.4.17:12.11.7,20:21:5.4.17:12.11.7,THB:29:28:43.42.41:31.32.47|
Structure:
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