Reaction Details
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Glutamate receptor ionotropic, kainate 4
Ligand
BDBM50002343
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_1341
Citation
Kamboj, RK; Schoepp, DD; Nutt, S; Shekter, L; Korczak, B; True, RA; Rampersad, V; Zimmerman, DM; Wosnick, MA Molecular cloning, expression, and pharmacological characterization of humEAA1, a human kainate receptor subunit. J Neurochem 62:1-9 (1994) [PubMed] Article More Info.:
Target
Name:
Glutamate receptor ionotropic, kainate 4
Synonyms:
GRIK | GRIK4 | GRIK4 protein | GRIK4_HUMAN | Glutamate-Kainate EAA1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
107246.86
Organism:
Homo sapiens (Human)
Description:
Q16099
Residue:
956
Sequence:
MPRVSAPLVLLPAWLVMVACSPHSLRIAAILDDPMECSRGERLSITLAKNRINRAPERLGKAKVEVDIFELLRDSEYETAETMCQILPKGVVAVLGPSSSPASSSIISNICGEKEVPHFKVAPEEFVKFQFQRFTTLNLHPSNTDISVAVAGILNFFNCTTACLICAKAECLLNLEKLLRQFLISKDTLSVRMLDDTRDPTPLLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNLEFSLQRMDSLVDDRVNILGFSIFNQSHAFFQEFAQSLNQSWQENCDHVPFTGPALSSALLFDAVYAVVTAVQELNRSQEIGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLTGHIEFNSKGQRSNYALKILQFTRNGFRQIGQWHVAEGLSMDSHLYASNISDTLFNTTLVVTTILENPYLMLKGNHQEMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDVPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSNYAFLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILKRKWWEGGKCPKEEDHRAKGLGMENIGGIFVVLICGLIVAIFMAMLEFLWTLRHSEATEVSVCQEMVTELRSIILCQDSIHPRRRRAAVPPPRPPIPEERRPRGTATLSNGKLCGAGEPDQLAQRLAQEAALVARGCTHIRVCPECRRFQGLRARPSPARSEESLEWEKTTNSSEPE
Inhibitor
Name:
BDBM50002343
Synonyms:
2-Methylamino-succinic acid | CHEMBL275325 | NMDA
Type:
Small organic molecule
Emp. Form.:
C5H9NO4
Mol. Mass.:
147.1293
SMILES:
CNC(CC(O)=O)C(O)=O
Structure:
