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Target
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Ligand
BDBM54327
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay
IC50
5457±327 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay PubChem Bioassay (2011)[AID] 
Target
Name:
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Synonyms:
CTDS1_HUMAN | CTDSP1 | NIF3 | NLIIF | SCP1 | carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29199.89
Organism:
Homo sapiens (Human)
Description:
gi_10864009
Residue:
261
Sequence:
MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGAPLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS
  
Inhibitor
Name:
BDBM54327
Synonyms:
2-[(6-bromanylquinazolin-4-yl)amino]-4-nitro-phenol;hydrochloride | 2-[(6-bromo-4-quinazolinyl)amino]-4-nitrophenol hydrochloride | 2-[(6-bromo-4-quinazolinyl)amino]-4-nitrophenol;hydrochloride | 2-[(6-bromoquinazolin-4-yl)amino]-4-nitro-phenol;hydrochloride | 2-[(6-bromoquinazolin-4-yl)amino]-4-nitrophenol;hydrochloride | MLS000690693 | SMR000301111 | cid_5711520
Type:
Small organic molecule
Emp. Form.:
C14H9BrN4O3
Mol. Mass.:
361.15
SMILES:
Oc1ccc(cc1Nc1ncnc2ccc(Br)cc12)[N+]([O-])=O
Structure:
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