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Target
Beta-lactamase
Ligand
BDBM83262
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA)
IC50
7425±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM83262
Synonyms:
MLS001065950 | N-butyl-2-(3-hexylsulfanyl-4-methoxy-phenyl)imidazo[1,2-a]pyrazin-3-amine | N-butyl-2-(3-hexylsulfanyl-4-methoxyphenyl)imidazo[1,2-a]pyrazin-3-amine | N-butyl-2-[3-(hexylthio)-4-methoxyphenyl]-3-imidazo[1,2-a]pyrazinamine | SMR000814612 | butyl-[2-[3-(hexylthio)-4-methoxy-phenyl]imidazo[1,2-a]pyrazin-3-yl]amine | cid_42601091
Type:
Small organic molecule
Emp. Form.:
C23H32N4OS
Mol. Mass.:
412.591
SMILES:
CCCCCCSc1cc(ccc1OC)-c1nc2cnccn2c1NCCCC
Structure:
Search PDB for entries with ligand similarity: