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Target
Beta-arrestin-1
Ligand
BDBM34233
Substrate
n/a
Meas. Tech.
Dose Response Assay for Inhibitors of the beta-Arrestin-Adaptor Protein 2 Interaction for Cherry Pick 1
IC50
1524±n/a nM
Citation
 PubChem, PC Dose Response Assay for Inhibitors of the beta-Arrestin-Adaptor Protein 2 Interaction for Cherry Pick 1 PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-arrestin-1
Synonyms:
ARR1 | ARRB1 | ARRB1_HUMAN | Arrestin, beta 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47062.57
Organism:
Homo sapiens (Human)
Description:
gi_13177715
Residue:
418
Sequence:
MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
  
Inhibitor
Name:
BDBM34233
Synonyms:
2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-benzo[d]isoselenazol-3-one(Ebselen) | 2-phenyl-1,2-benzisoselazol-3(2H)-one | 2-phenyl-1,2-benzoselenazol-3-one | 2-phenylbenzo[d][1,2]selenazol-3(2H)-one | CHEMBL51085 | EBSELEN | Ebselen (C5) | MLS000028488 | SMR000058445 | cid_3194 | med.21724, Compound 153
Type:
Small organic molecule
Emp. Form.:
C13H9NOSe
Mol. Mass.:
274.18
SMILES:
O=c1n([se]c2ccccc12)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: