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Target
D(2) dopamine receptor
Ligand
BDBM50000646
Substrate
n/a
Meas. Tech.
ChEBML_62093
Ki
1300±n/a nM
Citation
 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J (Aminoalkoxy)chromones. Selective sigma receptor ligands. J Med Chem 35:1526-35 (1992) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50000646
Synonyms:
6-{6-[4-(4-Chloro-phenyl)-piperazin-1-yl]-hexyloxy}-2-phenyl-chromen-4-one | CHEMBL38547
Type:
Small organic molecule
Emp. Form.:
C31H33ClN2O3
Mol. Mass.:
517.058
SMILES:
Clc1ccc(cc1)N1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CC1
Structure:
Search PDB for entries with ligand similarity: