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Target
Platelet-activating factor receptor
Ligand
BDBM50000712
Substrate
n/a
Meas. Tech.
ChEBML_155155
Ki
3250±n/a nM
Citation
 Guinn, DE; Summers, JB; Heyman, HR; Conway, RG; Rhein, DA; Albert, DH; Magoc, T; Carter, GW Synthesis and structure-activity relationships of a series of novel benzopyran-containing platelet activating factor antagonists. J Med Chem 35:2055-61 (1992) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50000712
Synonyms:
7-[4-(4-Fluoro-phenyl)-1-methyl-butyl]-10,10-dimethyl-3-prop-2-ynyl-2,3,4,10-tetrahydro-1H-9-oxa-3-aza-phenanthren-5-ol | CHEMBL303312 | TCMDC-124277
Type:
Small organic molecule
Emp. Form.:
C28H32FNO2
Mol. Mass.:
433.5576
SMILES:
CC(CCCc1ccc(F)cc1)c1cc(O)c2C3=C(CCN(CC#C)C3)C(C)(C)Oc2c1 |t:18|
Structure:
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