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Target
Delta-type opioid receptor
Ligand
BDBM50000805
Substrate
n/a
Meas. Tech.
ChEMBL_146452 (CHEMBL758727)
IC50
22.0±n/a nM
Citation
 Toth, G; Russell, KC; Landis, G; Kramer, TH; Fang, L; Knapp, R; Davis, P; Burks, TF; Yamamura, HI; Hruby, VJ Ring substituted and other conformationally constrained tyrosine analogues of [D-Pen2,D-Pen5]enkephalin with delta opioid receptor selectivity. J Med Chem 35:2384-91 (1992) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40577.25
Organism:
MOUSE
Description:
P32300
Residue:
372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50000805
Synonyms:
13-[(2-Amino-6-hydroxy-1,2,3,4,4a,8a-hexahydro-naphthalene-2-carbonyl)-amino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid | CHEMBL310742
Type:
Small organic molecule
Emp. Form.:
C32H43N5O7S2
Mol. Mass.:
673.843
SMILES:
CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@]2(N)CCC3CC(=O)C=CC3C2)C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O |c:20|
Structure:
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