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Target
Leukotriene B4 receptor 1
Ligand
BDBM50001610
Substrate
n/a
Meas. Tech.
ChEMBL_99649 (CHEMBL709307)
IC50
300±n/a nM
Citation
 Huang, FC; Chan, WK; Warus, JD; Morrissette, MM; Moriarty, KJ; Chang, MN; Travis, JJ; Mitchell, LS; Nuss, GW; Sutherland, CA 4-[2-[Methyl(2-phenethyl)amino]-2-oxoethyl]-8-(phenylmethoxy)-2- naphthalenecarboxylic acid: a high affinity, competitive, orally active leukotriene B4 receptor antagonist. J Med Chem 35:4253-5 (1992) [PubMed]  Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50001610
Synonyms:
7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy]-8-propyl-chroman-2-carboxylic acid | 7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy]-8-propyl-chroman-2-carboxylic acid (SC41930) | CGS 24115 | CHEMBL14823 | SC-41930
Type:
Small organic molecule
Emp. Form.:
C28H36O7
Mol. Mass.:
484.5812
SMILES:
CCCc1c(OCCCOc2ccc3CCC(Oc3c2CCC)C(O)=O)ccc(C(C)=O)c1OC
Structure:
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