Reaction Details Report a problem with these data
Target
Thromboxane A2 receptor
Ligand
BDBM50002760
Substrate
n/a
Meas. Tech.
ChEMBL_209575 (CHEMBL879433)
Ki
10±n/a nM
Citation
 Ohshima, E; Takami, H; Sato, H; Obase, H; Miki, I; Ishii, A; Karasawa, A; Kubo, K Non-prostanoid thromboxane A2 receptor antagonists with a dibenzoxepin ring system. 1. J Med Chem 35:3394-402 (1992) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50002760
Synonyms:
11-{2-[(3-Methyl-thiophene-2-carbonyl)-amino]-ethylsulfanyl}-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid | CHEMBL115924
Type:
Small organic molecule
Emp. Form.:
C23H21NO4S2
Mol. Mass.:
439.547
SMILES:
Cc1ccsc1C(=O)NCCSC1c2ccccc2COc2ccc(cc12)C(O)=O
Structure:
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