Reaction Details Report a problem with these data
Target
Thromboxane A2 receptor
Ligand
BDBM50002771
Substrate
n/a
Meas. Tech.
ChEMBL_209575 (CHEMBL879433)
Ki
20±n/a nM
Citation
 Ohshima, E; Takami, H; Sato, H; Obase, H; Miki, I; Ishii, A; Karasawa, A; Kubo, K Non-prostanoid thromboxane A2 receptor antagonists with a dibenzoxepin ring system. 1. J Med Chem 35:3394-402 (1992) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50002771
Synonyms:
11-[2-(4-Trifluoromethyl-benzenesulfonylamino)-ethylsulfanyl]-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid | CHEMBL114363
Type:
Small organic molecule
Emp. Form.:
C24H20F3NO5S2
Mol. Mass.:
523.545
SMILES:
OC(=O)c1ccc2OCc3ccccc3C(SCCNS(=O)(=O)c3ccc(cc3)C(F)(F)F)c2c1
Structure:
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