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Target
Adenosine receptor A1
Ligand
BDBM50009509
Substrate
n/a
Meas. Tech.
ChEBML_29278
EC50
12303±n/a nM
Citation
 Niiya, K; Olsson, RA; Thompson, RD; Silvia, SK; Ueeda, M 2-(N'-alkylidenehydrazino)adenosines: potent and selective coronary vasodilators. J Med Chem 35:4557-61 (1993) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor | AA1R_CAVPO | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor | Adenosine Receptor A1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36501.39
Organism:
GUINEA PIG
Description:
ADENOSINE A1 ADORA1 GUINEA PIG::P47745
Residue:
326
Sequence:
MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD
  
Inhibitor
Name:
BDBM50009509
Synonyms:
(CGS 22,492) 2-[6-Amino-2-(2-cyclohexyl-ethylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol | 2-[6-Amino-2-(2-cyclohexyl-ethylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol | CHEMBL87459
Type:
Small organic molecule
Emp. Form.:
C18H28N6O4
Mol. Mass.:
392.4527
SMILES:
Nc1nc(NCCC2CCCCC2)nc2n(cnc12)C1O[C@H](CO)[C@@H](O)[C@H]1O
Structure:
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