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Target
Thromboxane A2 receptor
Ligand
BDBM50004558
Substrate
n/a
Meas. Tech.
ChEBML_209589
IC50
25000±n/a nM
Citation
 Komiotis, D; Lim, CT; Dieter, JP; Le Breton, GC; Venton, DL PgH2 analogs as potential antiplatelet derivatives. J Med Chem 35:3033-9 (1992) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50004558
Synonyms:
7-(6-Hexylaminomethyl-2-oxa-bicyclo[2.2.1]hept-5-yl)-hept-5-enoic acid | CHEMBL102584
Type:
Small organic molecule
Emp. Form.:
C20H35NO3
Mol. Mass.:
337.4968
SMILES:
CCCCCCNC[C@H]1C2CC(CO2)[C@@H]1C\C=C/CCCC(O)=O |TLB:15:14:10:13.12,THB:7:8:10:13.12|
Structure:
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