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Reaction Details
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TargetProstanoid TP receptor
LigandBDBM50005098
Substrate/Competitorn/a
Meas. Tech.ChEBML_209761
IC50 1400±n/a nM
Citation Fukumoto, SShiraishi, MTerashita, ZAshida, YInada, Y Synthesis and thromboxane A2/prostaglandin H2 receptor antagonistic activity of phenol derivatives. J Med Chem35:2202-9 (1992) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Prostanoid TP receptor
Name:Thromboxane A2 receptor
Synonyms:TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:Enyzme
Mol. Mass.:37445.28
Organism:Homo sapiens (Human)
Description:P21731
Residue:343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50005098
NameBDBM50005098
Synonyms:7-(4-Fluoro-phenyl)-7-(2,4,5-trimethyl-3,6-dioxo-cyclohexa-1,4-dienyl)-heptanoic acid | CHEMBL71222
TypeSmall organic molecule
Emp. Form.C22H25FO4
Mol. Mass.372.4299
SMILESCc1c(C)c(O)c(C(=CCCCCC(O)=O)c2ccc(F)cc2)c(C)c1O |w:8.8|
Structure
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