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Target
Thromboxane A2 receptor
Ligand
BDBM50005113
Substrate
n/a
Meas. Tech.
ChEBML_209761
IC50
200±n/a nM
Citation
 Fukumoto, S; Shiraishi, M; Terashita, Z; Ashida, Y; Inada, Y Synthesis and thromboxane A2/prostaglandin H2 receptor antagonistic activity of phenol derivatives. J Med Chem 35:2202-9 (1992) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50005113
Synonyms:
7-(2,5-Dihydroxy-3,4,6-trimethyl-phenyl)-7-(4-fluoro-phenyl)-heptanoic acid | CHEMBL70314
Type:
Small organic molecule
Emp. Form.:
C22H27FO4
Mol. Mass.:
374.4458
SMILES:
Cc1c(C)c(O)c(C(CCCCCC(O)=O)c2ccc(F)cc2)c(C)c1O
Structure:
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