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Target
Aromatic-L-amino-acid decarboxylase
Ligand
BDBM50005740
Substrate
n/a
Meas. Tech.
ChEMBL_58142 (CHEMBL672886)
Ki
630000±n/a nM
Citation
 Ahmad, S; Phillips, RS; Stammer, CH Inhibition of pig kidney L-aromatic amino acid decarboxylase by 2,3-methano-m-tyrosines. J Med Chem 35:1410-7 (1992) [PubMed]  Article 
Target
Name:
Aromatic-L-amino-acid decarboxylase
Synonyms:
DDC | DDC_PIG | DOPA decarboxylase
Type:
PROTEIN
Mol. Mass.:
53939.21
Organism:
Sus scrofa
Description:
ChEMBL_59433
Residue:
486
Sequence:
MNASDFRRRGKEMVDYMADYLEGIEGRQVYPDVQPGYLRPLIPATAPQEPDTFEDILQDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLQLPEAFLAGEAGEGGGVIQGSASEATLVALLAARTKVVRRLQAASPGLTQGAVLEKLVAYASDQAHSSVERAGLIGGVKLKAIPSDGKFAMRASALQEALERDKAAGLIPFFVVATLGTTSCCSFDNLLEVGPICHEEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKRRTDLTGAFKLDPVYLKHSHQGSGLITDYRHWQLPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFEAFVLQDPRFEVCAEVTLGLVCFRLKGSDGLNEALLERINSARKIHLVPCRLRGQFVLRFAICSRKVESGHVRLAWEHIRGLAAELLAAEEGKAEIKS
  
Inhibitor
Name:
BDBM50005740
Synonyms:
(+)-1-Amino-2-(3-hydroxy-phenyl)-cyclopropa necarboxylic acid | (-)-1-Amino-2-(3-hydroxy-phenyl)-cyclopropanecarboxylic acid | CHEMBL30857
Type:
Small organic molecule
Emp. Form.:
C10H11NO3
Mol. Mass.:
193.1992
SMILES:
NC1(CC1c1cccc(O)c1)C(O)=O
Structure:
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