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Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM50006248
Substrate
n/a
Meas. Tech.
ChEMBL_222719 (CHEMBL844387)
Ki
220000±n/a nM
Citation
 De Amici, M; Dallanoce, C; De Micheli, C; Grana, E; Barbieri, A; Ladinsky, H; Schiavi, G; Zonta, F Synthesis and pharmacological investigation of the enantiomers of muscarone and allomuscarone. J Med Chem 35:1915-20 (1992) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51390.46
Organism:
RAT
Description:
P08482
Residue:
460
Sequence:
MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
  
Inhibitor
Name:
BDBM50006248
Synonyms:
(4-Hydroxy-5-methyl-tetrahydro-furan-2-ylmethyl)-trimethyl-ammonium; iodide | CHEMBL301699
Type:
Small organic molecule
Emp. Form.:
C9H20NO2
Mol. Mass.:
174.2601
SMILES:
C[C@H]1O[C@@H](C[N+](C)(C)C)C[C@@H]1O
Structure:
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