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Target
Kappa-type opioid receptor
Ligand
BDBM50007002
Substrate
n/a
Meas. Tech.
ChEMBL_145370 (CHEMBL753138)
IC50
56±n/a nM
Citation
 Freeman, JP; Michalson, ET; D'Andrea, SV; Baczynskyj, L; Von Voigtlander, PF; Lahti, RA; Smith, MW; Lawson, CF; Scahill, TA; Mizsak, SA Naphtho and benzo analogues of the kappa opioid agonist trans-(+/-)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl] benzeneacetamide. J Med Chem 34:1891-6 (1991) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
KOR-1 | MSL-1 | OPIATE Kappa | OPRK_MOUSE | Oprk1
Type:
Enzyme
Mol. Mass.:
42656.78
Organism:
Mus musculus (Mouse)
Description:
P33534
Residue:
380
Sequence:
MESPIQIFRGDPGPTCSPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLESAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRVRNTVQDPASMRDVGGMNKPV
  
Inhibitor
Name:
BDBM50007002
Synonyms:
3,4-Dichloro-N-(3-dimethylamino-1,2,3,4-tetrahydro-naphthalen-2-yl)-N-methyl-benzamide | CHEMBL296184
Type:
Small organic molecule
Emp. Form.:
C20H22Cl2N2O
Mol. Mass.:
377.307
SMILES:
CN(C)[C@@H]1Cc2ccccc2C[C@H]1N(C)C(=O)c1ccc(Cl)c(Cl)c1
Structure:
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