Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM50007476
Substrate
n/a
Meas. Tech.
ChEBML_41681
EC50
130±n/a nM
Citation
 Adejare, A; Nie, JY; Hebel, D; Brackett, LE; Choi, O; Gusovsky, F; Padgett, WL; Daly, JW; Creveling, CR; Kirk, KL Effect of fluorine substitution on the adrenergic properties of 3-(tert-butylamino)-1-(3,4-dihydroxyphenoxy)-2-propanol. J Med Chem 34:1063-8 (1991) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2_CAVPO | Adrb2 | adrenergic Beta2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46993.24
Organism:
GUINEA PIG
Description:
adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4
Residue:
418
Sequence:
MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKDAINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRFHTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNGKTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
  
Inhibitor
Name:
BDBM50007476
Synonyms:
4-(3-tert-Butylamino-2-hydroxy-propoxy)-benzene-1,2-diol | CHEMBL266619
Type:
Small organic molecule
Emp. Form.:
C13H21NO4
Mol. Mass.:
255.3101
SMILES:
CC(C)(C)NCC(O)COc1ccc(O)c(O)c1
Structure:
Search PDB for entries with ligand similarity: