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TargetTACR3
LigandBDBM50007962
Substrate/Competitorn/a
Meas. Tech.ChEMBL_141792
EC50 0.900000±n/a nM
Citation Roubini, ELaufer, RGilon, CSelinger, ZRoques, BPChorev, M Pseudopeptide analogues of substance P and leucine enkephalinamide containing the psi (CH2O) modification: synthesis and biological activity. J Med Chem34:2430-8 (1991) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
TACR3
Name:Neurokinin 3 receptor
Synonyms:Neurokinin NK3 | Neuromedin-K receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:49456.44
Organism:GUINEA PIG
Description:Neurokinin NK3 TACR3 GUINEA PIG::P30098
Residue:440
Sequence:
MASPAGNLSAWPGWGWPPPAALRNLTSSPAPTASPSPAPSWTPSPRPGPAHPFLQPPWAV
ALWSLAYGAVVAVAVLGNLVVIWIVLAHKRMRTVTNSFLVNLAFADAAMAALNALVNFIY
ALHGEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATRIVIG
SIWILAFLLAFPQCLYSKIKVMPGRTLCYVQWPEGSRQHFTYHMIVIVLVYCFPLLIMGI
TYTIVGITLWGGEIPGDTCDKYQEQLKAKRKVVKMMIIVVVTFAICWLPYHIYFILTAIY
QQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIHVSSYDEL
ELKATRLHPMRQSSLYTVTRMESMSVVFDSNDGDSARSSHQKRGTTRDVGSNVCSRRNSK
STSTTASFVSSSHMSVEEGS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50007962
NameBDBM50007962
Synonyms:CHEMBL81919 | pGlu6-Phe-NMePhe-Gly-Leu-Met-NH2
TypeSmall organic molecule
Emp. Form.C37H51N7O7S
Mol. Mass.737.909
SMILESCSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCC(=O)N1)C(N)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a