Reaction Details Report a problem with these data
Target
Aminopeptidase B
Ligand
BDBM50008427
Substrate
n/a
Meas. Tech.
ChEBML_36049
Ki
130000±n/a nM
Citation
 Ocain, TD; Rich, DH alpha-Keto amide inhibitors of aminopeptidases. J Med Chem 35:451-6 (1992) [PubMed]  Article 
Target
Name:
Aminopeptidase B
Synonyms:
AMPB_HUMAN | APB | Aminopeptidase | Ap-B | Arginine aminopeptidase | Arginyl aminopeptidase | RNPEP
Type:
PROTEIN
Mol. Mass.:
72586.33
Organism:
Homo sapiens (Human)
Description:
ChEMBL_36048
Residue:
650
Sequence:
MASGEHSPGSGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVLLTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGPNKFFFQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAISPWKTYQLVYFLDKILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGKQKYTLPLYHAMMGGSEVAQTLAKETFASTASQLHSNVVNYVQQIVAPKGS
  
Inhibitor
Name:
BDBM50008427
Synonyms:
5-Amino-2,7-dimethyl-4-oxo-octanoic acid | CHEMBL341941
Type:
Small organic molecule
Emp. Form.:
C10H19NO3
Mol. Mass.:
201.2628
SMILES:
CC(C)C[C@H](N)C(=O)CC(C)C(O)=O
Structure:
Search PDB for entries with ligand similarity: