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Target
Kappa-type opioid receptor
Ligand
BDBM50008981
Substrate
n/a
Meas. Tech.
ChEBML_145208
IC50
>10000±n/a nM
Citation
 Bagley, JR; Thomas, SA; Rudo, FG; Spencer, HK; Doorley, BM; Ossipov, MH; Jerussi, TP; Benvenga, MJ; Spaulding, T New 1-(heterocyclylalkyl)-4-(propionanilido)-4-piperidinyl methyl ester and methylene methyl ether analgesics. J Med Chem 34:827-41 (1991) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42744.99
Organism:
Cavia porcellus (domestic guinea pig)
Description:
P41144
Residue:
380
Sequence:
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRNVDGVNKPV
  
Inhibitor
Name:
BDBM50008981
Synonyms:
CHEMBL169587 | N-{1-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-4-methoxymethyl-piperidin-4-yl}-N-phenyl-propionamide
Type:
Small organic molecule
Emp. Form.:
C26H31N3O4
Mol. Mass.:
449.542
SMILES:
CCC(=O)N(c1ccccc1)C1(COC)CCN(CCN2C(=O)c3ccccc3C2=O)CC1
Structure:
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