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Target
Vesicular acetylcholine transporter
Ligand
BDBM50009604
Substrate
n/a
Meas. Tech.
ChEBML_213552
IC50
115±n/a nM
Citation
 Efange, SM; Michelson, RH; Dutta, AK; Parsons, SM Acyclic analogues of 2-(4-phenylpiperidino)cyclohexanol (vesamicol): conformationally mobile inhibitors of vesicular acetylcholine transport. J Med Chem 34:2638-43 (1991) [PubMed]  Article 
Target
Name:
Vesicular acetylcholine transporter
Synonyms:
TorVAChT | VACHT_TETCF | VAChT
Type:
PROTEIN
Mol. Mass.:
56111.93
Organism:
Torpedo californica
Description:
ChEMBL_1503355
Residue:
515
Sequence:
MGVTMAVGLAKAAMGKISSAIGERSKRISGAMNEPRRKRKILLVIVCIAMLLDNMLYMVIVPIIPNYLETIRTYKLVYITTPSNGTNGSLLNSTQRAVLERNPNANEDIQIGVLFASKAILQLLSNPFTGTFIDRVGYDIPLLIGLTIMFFSTITFAFGESYAVLFAARSLQGLGSAFADTSGIAMIADKYTEESERTQALGIALAFISFGSLVAPPFGGVLYQFAGKWVPFLVLSFVCLLDGILLLMVVTPFASRTRENMLQGTPIYKLMIDPYIAVVAGALTTCNIPLAFLEPTISNWMKKTMNASEWQMGITWLPAFFPHILGVYITVKLAAKYPNYQWFYGAVGLVIIGASSCTIPACRNFEELIIPLCALCFGIALVDTALLPTLAFLVDIRYVSVYGSVYAIADISYSVAYALGPIMAGQIVHDLGFVQLNLGMGLVNILYAPALLFLRNVCQMKPSLSERNILLEEGPKGLYDTIIMEERKAAKEPHGSSSGNHSVHAVLSDQEGYSE
  
Inhibitor
Name:
BDBM50009604
Synonyms:
1-(3-Methoxy-phenyl)-3-(4-phenyl-piperidin-1-yl)-propan-2-ol | CHEMBL90556
Type:
Small organic molecule
Emp. Form.:
C21H27NO2
Mol. Mass.:
325.4446
SMILES:
COc1cccc(CC(O)CN2CCC(CC2)c2ccccc2)c1
Structure:
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