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TargetAldose reductase
LigandBDBM50009978
Substrate/Competitorn/a
Meas. Tech.ChEBML_32094
IC50 6700±n/a nM
Citation DeRuiter, JDavis, RAWandrekar, VGMayfield, CA Relative structure-inhibition analyses of the N-benzoyl and N-(phenylsulfonyl) amino acid aldose reductase inhibitors. J Med Chem34:2120-6 (1991) [PubMed]  Article
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Aldose reductase
Name:Aldose reductase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:35797.87
Organism:Rattus norvegicus
Description:ChEMBL_1512484
Residue:316
Sequence:
MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQ
EKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGP
DYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKP
AVNQIECHPYLTQEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAK
YNKTTAQVLIRFPIQRNLVVIPKSVTPARIAENFKVFDFELSNEDMATLLSYNRNWRVCA
LMSCAKHKDYPFHAEV
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BDBM50009978
NameBDBM50009978
Synonyms:CHEMBL66711 | [(4-Methoxy-benzoyl)-methyl-amino]-acetic acid
TypeSmall organic molecule
Emp. Form.C11H13NO4
Mol. Mass.223.2252
SMILESCOc1ccc(cc1)C(=O)N(C)CC(O)=O
Structure
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n/a