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TargetAldose reductase
LigandBDBM50009993
Substrate/Competitorn/a
Meas. Tech.ChEBML_32094
IC50 45000±n/a nM
Citation DeRuiter, JDavis, RAWandrekar, VGMayfield, CA Relative structure-inhibition analyses of the N-benzoyl and N-(phenylsulfonyl) amino acid aldose reductase inhibitors. J Med Chem34:2120-6 (1991) [PubMed]  Article
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Aldose reductase
Name:Aldose reductase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:35797.87
Organism:Rattus norvegicus
Description:ChEMBL_1512484
Residue:316
Sequence:
MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQ
EKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGP
DYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKP
AVNQIECHPYLTQEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAK
YNKTTAQVLIRFPIQRNLVVIPKSVTPARIAENFKVFDFELSNEDMATLLSYNRNWRVCA
LMSCAKHKDYPFHAEV
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  Blast E-value cutoff:
BDBM50009993
NameBDBM50009993
Synonyms:CHEMBL67410 | [4-(3-Phenyl-propionylamino)-benzoylamino]-acetic acid
TypeSmall organic molecule
Emp. Form.C18H18N2O4
Mol. Mass.326.3465
SMILESOC(=O)CNC(=O)c1ccc(NC(=O)CCc2ccccc2)cc1
Structure
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n/a