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Target
Beta-2 adrenergic receptor
Ligand
BDBM50010553
Substrate
n/a
Meas. Tech.
ChEBML_196404
Ki
2170±n/a nM
Citation
 Leftheris, K; Goodman, M Synthesis and beta-adrenergic antagonist activity of stereoisomeric practolol and propranolol derivatives. J Med Chem 33:216-23 (1990) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2_MOUSE | Adrb2 | Adrb2r | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor | Beta-adrenergic receptor
Type:
PROTEIN
Mol. Mass.:
47002.38
Organism:
Mus musculus
Description:
ChEMBL_196404
Residue:
418
Sequence:
MGPHGNDSDFLLAPNGSRAPDHDVTQERDEAWVVGMAILMSVIVLAIVFGNVLVITAIAKFERLQTVTNYFIISLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKKAIDCYTEETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNLSQVEQDGRSGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIRDNLIPKEVYILLNWLGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSSKTYGNGYSSNSNGRTDYTGEPNTCQLGQEREQELLCEDPPGMEGFVNCQGTVPSLSVDSQGRNCSTNDSPL
  
Inhibitor
Name:
BDBM50010553
Synonyms:
6-[3-(4-Acetylamino-phenoxy)-2-hydroxy-propylamino]-heptanoic acid (4-trifluoromethyl-phenyl)-amide(R,R) | CHEMBL421682
Type:
Small organic molecule
Emp. Form.:
C25H32F3N3O4
Mol. Mass.:
495.5345
SMILES:
C[C@H](CCCCC(=O)Nc1ccc(cc1)C(F)(F)F)NC[C@@H](O)COc1ccc(NC(C)=O)cc1
Structure:
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