Reaction Details Report a problem with these data
Target
Platelet-activating factor receptor
Ligand
BDBM50011109
Substrate
n/a
Meas. Tech.
ChEMBL_177423 (CHEMBL784402)
IC50
15±n/a nM
Citation
 Bartrolí, J; Carceller, E; Merlos, M; García-Rafanell, J; Forn, J Disubstituted tetrahydrofurans and dioxolanes and PAF antagonists. J Med Chem 34:373-86 (1991) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50011109
Synonyms:
2-{[Acetyl-(4-hexadecyloxymethyl-[1,3]dioxolan-2-ylmethoxycarbonyl)-amino]-methyl}-1-ethyl-pyridinium; chloride | 2-{[Acetyl-(4-hexadecyloxymethyl-[1,3]dioxolan-2-ylmethoxycarbonyl)-amino]-methyl}-1-ethyl-pyridinium; iodide | CHEMBL338441
Type:
Small organic molecule
Emp. Form.:
C32H55N2O6
Mol. Mass.:
563.7884
SMILES:
CCCCCCCCCCCCCCCCOCC1COC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)O1
Structure:
Search PDB for entries with ligand similarity: