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TargetHuman immunodeficiency virus type 1 protease
LigandBDBM50011688
Substrate/Competitorn/a
Meas. Tech.ChEBML_158641
IC50 16±n/a nM
Citation Rich, DHSun, CQVara Prasad, JVPathiasseril, AToth, MVMarshall, GRClare, MMueller, RAHouseman, K Effect of hydroxyl group configuration in hydroxyethylamine dipeptide isosteres on HIV protease inhibition. Evidence for multiple binding modes. J Med Chem34:1222-5 (1991) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Human immunodeficiency virus type 1 protease
Name:Human immunodeficiency virus type 1 protease
Synonyms:Pol polyprotein
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:n/a
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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  Blast E-value cutoff:
BDBM50011688
NameBDBM50011688
Synonyms:Boc-Asn-Phe-HEA(R)-Pro-Ile-Val-OMe | CHEMBL276962 | CHEMBL3349554
TypeSmall organic molecule
Emp. Form.C36H58N6O9
Mol. Mass.718.8805
SMILESCC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)OC(C)(C)C)C(=O)N[C@@H](C(C)C)C(=O)OC
Structure
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