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TargetMu-type opioid receptor
LigandBDBM50274740
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1714215
IC50 5.0±n/a nM
Citation Willemse, TEiselt, EHollanders, KSchepens, Wvan Vlijmen, HWTChung, NNBlais, VHolleran, BLongpré, JMSchiller, PWMaes, BUWSarret, PGendron, LBallet, S Chemical space screening around Phe Bioorg Med Chem Lett28:2320-2323 (2018) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Opioid receptors; mu and delta
Synonyms:M-OR-1 | MOR-1 | Mor | OPIATE Mu | Oprm | Oprm1
Type:Enzyme Catalytic Domain
Mol. Mass.:44431.62
Organism:MOUSE
Description:OPIATE Mu OPRM1 MOUSE::P42866
Residue:398
Sequence:
MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50274740
NameBDBM50274740
Synonyms:CHEMBL4128463
TypeSmall organic molecule
Emp. Form.C32H42N8O5S
Mol. Mass.650.791
SMILESCc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccsc1)C(=O)NCC(N)=O |r|
Structure
n/a