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Target
Cholecystokinin receptor type A
Ligand
BDBM50005459
Substrate
n/a
Meas. Tech.
ChEMBL_49575 (CHEMBL661829)
IC50
12400±n/a nM
Citation
 Kerwin, JF; Nadzan, AM; Kopecka, H; Lin, CW; Miller, T; Witte, D; Burt, S Hybrid cholecystokinin (CCK) antagonists: new implications in the design and modification of CCK antagonists. J Med Chem 32:739-42 (1989) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_CAVPO | Cholecystokinin A receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor
Type:
n/a
Mol. Mass.:
48229.77
Organism:
Cavia porcellus
Description:
n/a
Residue:
430
Sequence:
MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRSSSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50005459
Synonyms:
4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-butyric acid | CHEMBL9485 | CR 1409
Type:
Small organic molecule
Emp. Form.:
C22H32Cl2N2O4
Mol. Mass.:
459.406
SMILES:
CCCCCN(CCCCC)C(=O)[C@@H](CCC(O)=O)NC(=O)c1ccc(Cl)c(Cl)c1
Structure:
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