Reaction Details Report a problem with these data
Target
Gamma-aminobutyric acid receptor subunit gamma-1
Ligand
BDBM50021186
Substrate
n/a
Meas. Tech.
ChEBML_68602
IC50
400±n/a nM
Citation
 Krogsgaard-Larsen, P; Nielsen, L; Falch, E; Curtis, DR GABA agonists. Resolution, absolute stereochemistry, and enantioselectivity of (S)-(+)- and (R)-(-)-dihydromuscimol. J Med Chem 28:1612-7 (1985) [PubMed]  Article 
Target
Name:
Gamma-aminobutyric acid receptor subunit gamma-1
Synonyms:
Benzodiazepine receptors | Benzodiazepine receptors; peripheral & central | GABA receptor gamma-1 subunit | GBRG1_RAT | Gabrg1
Type:
PROTEIN
Mol. Mass.:
53557.84
Organism:
Rattus norvegicus
Description:
ChEMBL_193817
Residue:
465
Sequence:
MGSGKVFLFSPSLLWSQTRGVRLIFLLLTLHLGNCIDKADDEDDEDLTMNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNSTEISHTISGDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNNKGKTTRDRKLKSKTSVSPGLHAGSTLIPMNNISMPQGEDDYGYQCLEGKDCATFFCCFEDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYLYL
  
Inhibitor
Name:
BDBM50021186
Synonyms:
4-Amino-3-hydroxy-butyric acid | CHEMBL296263 | S(+)-4-amino-3-hydroxybutanoic acid
Type:
Small organic molecule
Emp. Form.:
C4H9NO3
Mol. Mass.:
119.1192
SMILES:
NC[C@@H](O)CC(O)=O
Structure:
Search PDB for entries with ligand similarity: