Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50023495
Substrate
n/a
Meas. Tech.
ChEBML_28547
IC50
21±n/a nM
Citation
 Francis, JE; Cash, WD; Psychoyos, S; Ghai, G; Wenk, P; Friedmann, RC; Atkins, C; Warren, V; Furness, P; Hyun, JL Structure-activity profile of a series of novel triazoloquinazoline adenosine antagonists. J Med Chem 31:1014-20 (1988) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50023495
Synonyms:
2-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylamino)-ethanol | CHEMBL268867
Type:
Small organic molecule
Emp. Form.:
C15H12ClN5O2
Mol. Mass.:
329.741
SMILES:
OCCNc1nc2ccc(Cl)cc2c2nc(nn12)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: