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Target
CDGSH iron-sulfur domain-containing protein 1
Ligand
BDBM50350486
Substrate
n/a
Meas. Tech.
ChEMBL_609914 (CHEMBL1074776)
IC50
900±n/a nM
Citation
 Geldenhuys, WJ; Funk, MO; Barnes, KF; Carroll, RT Structure-based design of a thiazolidinedione which targets the mitochondrial protein mitoNEET. Bioorg Med Chem Lett 20:819-23 (2010) [PubMed]  Article 
Target
Name:
CDGSH iron-sulfur domain-containing protein 1
Synonyms:
CDGSH iron-sulfur domain-containing protein 1 | CISD1_RAT | Cisd1 | MitoNEET
Type:
PROTEIN
Mol. Mass.:
12102.37
Organism:
Rattus norvegicus
Description:
ChEMBL_108443
Residue:
108
Sequence:
MGLSSDSPVRVEWIAAVTFAAGTAALGYLAYKKFYAKESRTKAMVNLQIQKDNPKVVHAFDMEDLGDKAVYCRCWRSKKFPFCDGAHIKHNEETGDNVGPLIIKKKET
  
Inhibitor
Name:
BDBM50350486
Synonyms:
CHEMBL602048
Type:
Small organic molecule
Emp. Form.:
C18H25NO3S
Mol. Mass.:
335.461
SMILES:
CC(C)(C)c1cc(Cc2sc(=O)[nH]c2O)cc(c1O)C(C)(C)C
Structure:
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