Reaction Details Report a problem with these data
Target
Acetolactate synthase, chloroplastic
Ligand
BDBM50486243
Substrate
n/a
Meas. Tech.
ChEMBL_893671 (CHEMBL3051049)
Ki
260±n/a nM
Citation
 Shang, J; Wang, WM; Li, YH; Song, HB; Li, ZM; Wang, JG Synthesis, crystal structure, in vitro acetohydroxyacid synthase inhibition, in vivo herbicidal activity, and 3D-QSAR of new asymmetric aryl disulfides. J Agric Food Chem 60:8286-93 (2012) [PubMed]  Article 
Target
Name:
Acetolactate synthase, chloroplastic
Synonyms:
AHAS | ALS | Acetolactate synthase | CSR1 | ILVB_ARATH | TZP5
Type:
PROTEIN
Mol. Mass.:
72585.19
Organism:
Arabidopsis thaliana
Description:
ChEMBL_934103
Residue:
670
Sequence:
MAAATTTTTTSSSISFSTKPSPSSSKSPLPISRFSLPFSLNPNKSSSSSRRRGIKSSSPSSISAVLNTTTNVTTTPSPTKPTKPETFISRFAPDQPRKGADILVEALERQGVETVFAYPGGASMEIHQALTRSSSIRNVLPRHEQGGVFAAEGYARSSGKPGICIATSGPGATNLVSGLADALLDSVPLVAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVMDVEDIPRIIEEAFFLATSGRPGPVLVDVPKDIQQQLAIPNWEQAMRLPGYMSRMPKPPEDSHLEQIVRLISESKKPVLYVGGGCLNSSDELGRFVELTGIPVASTLMGLGSYPCDDELSLHMLGMHGTVYANYAVEHSDLLLAFGVRFDDRVTGKLEAFASRAKIVHIDIDSAEIGKNKTPHVSVCGDVKLALQGMNKVLENRAEELKLDFGVWRNELNVQKQKFPLSFKTFGEAIPPQYAIKVLDELTDGKAIISTGVGQHQMWAAQFYNYKKPRQWLSSGGLGAMGFGLPAAIGASVANPDAIVVDIDGDGSFIMNVQELATIRVENLPVKVLLLNNQHLGMVMQWEDRFYKANRAHTFLGDPAQEDEIFPNMLLFAAACGIPAARVTKKADLREAIQTMLDTPGPYLLDVICPHQEHVLPMIPSGGTFNDVITEGDGRIKY
  
Inhibitor
Name:
BDBM50486243
Synonyms:
MONOSULFURON ESTER
Type:
Small organic molecule
Emp. Form.:
C14H14N4O5S
Mol. Mass.:
350.35
SMILES:
COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nccc(C)n1
Structure:
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