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Target
D(2) dopamine receptor
Ligand
BDBM50011261
Substrate
n/a
Meas. Tech.
ChEMBL_61457 (CHEMBL670884)
Ki
30±n/a nM
Citation
 Liu, Y; Yu, H; Mohell, N; Nordvall, G; Lewander, T; Hacksell, U Derivatives of cis-2-amino-8-hydroxy-1-methyltetralin: mixed 5-HT1A-receptor agonists and dopamine D2-receptor antagonists. J Med Chem 38:150-60 (1995) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50011261
Synonyms:
(+)7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride | (-)7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride | 7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride | CHEMBL43475 | CHEMBL544757
Type:
Small organic molecule
Emp. Form.:
C17H27NO
Mol. Mass.:
261.4024
SMILES:
CCCN(CCC)[C@@H]1CCc2cccc(O)c2[C@@H]1C
Structure:
Search PDB for entries with ligand similarity: