Reaction Details Report a problem with these data
Target
Dipeptidyl peptidase 3
Ligand
BDBM25756
Substrate
n/a
Meas. Tech.
ChEMBL_913307 (CHEMBL3062799)
Ki
230000±n/a nM
Citation
 Dhanda, S; Singh, J; Singh, H Goat brain enkephalin degrading enzyme: interaction with analgesic and antihypertensive drugs Med Chem Res 20:1294-7 (2011)    Article 
Target
Name:
Dipeptidyl peptidase 3
Synonyms:
3.4.14.4 | Dipeptidyl aminopeptidase III | Dipeptidyl peptidase 3 | Dipeptidyl peptidase III | M91_14005
Type:
PROTEIN
Mol. Mass.:
82027.05
Organism:
Bos mutus
Description:
ChEMBL_117383
Residue:
730
Sequence:
MADTQYILPNDIGVSSLDCREAFRLLSSTERLYAHYLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSEAAQQHPEEVRGLWQICGELMFSLESRLRHLGLGKEGITTYFSGNCTMEDAKLAQDFLDSQNLSAYNTRLFKEVGQDGKPSYEVRLASVLGTEPNLDSEMNSKLKSYEFQGSHFRVTRGDYAPILQKVVEQLEKAKAYAANSHQEQMLAQYIESFTQGSIEAHKKGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAMVNKAMSAKFEWLVASAEQLLKELPWPPAFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQREKLTFLEEEDKDLYIRWKGPSFDVQVGLHELLGHGSGKLFMQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPRVLEIFGFEGADAEDVVYVNWLNMVRAGLLALEFYTPEASSWRQAHMQARFVILRVLLEAGEGLVTVTPTTGSDGRPDARVRLDRDKIRTVGKPALERFLRRLQVLKSTGDVAGGRALYEGYAAVTDAPPECFLSLRDTVLLRKEARKLIVQPNTRLEGSEVQLLEYEASAAGLIRSFSERFLEDGPELEKILTQLATADAQCWKGPQ
  
Inhibitor
Name:
BDBM25756
Synonyms:
(2R,3R)-2,3-dihydroxysuccinic acid;1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol | Betalok | CHEMBL13 | Metoprolol | Spesicor | Spesikor | metoprolol tartrate | {2-hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl}(propan-2-yl)amine
Type:
Small organic molecule
Emp. Form.:
C15H25NO3
Mol. Mass.:
267.3639
SMILES:
COCCc1ccc(OCC(O)CNC(C)C)cc1
Structure:
Search PDB for entries with ligand similarity: