Reaction Details Report a problem with these data
Target
Acetylcholine receptor subunit beta-like 2
Ligand
BDBM50487981
Substrate
n/a
Meas. Tech.
ChEMBL_917696 (CHEMBL3052327)
IC50
160±n/a nM
Citation
 Zhang, A; Kayser, H; Maienfisch, P; Casida, JE Insect nicotinic acetylcholine receptor: conserved neonicotinoid specificity of [(3)H]imidacloprid binding site. J Neurochem 75:1294-303 (2000) [PubMed]  Article 
Target
Name:
Acetylcholine receptor subunit beta-like 2
Synonyms:
ACH4_DROME | Acetylcholine receptor subunit beta-like 2 | Acr96Ac | AcrF | Nicotinic acetylcholine receptor beta 2 | SBD | nAChRbeta2 | nAcRbeta-96
Type:
PROTEIN
Mol. Mass.:
60124.10
Organism:
Drosophila melanogaster
Description:
ChEMBL_109085
Residue:
519
Sequence:
MWHWSLLCVFLLVPLANSTAPISFEANPDTKRLYDDLLSNYNRLIRPVVNNTETLTVWLGLKLSQLIEVNLKNQVMTTNLWVKQRWFDYKLRWDPEEYGGVEQLYVPSEHIWVPDIVLYNNWDGNYEVTLMTKATLKYTGEVFWEPPAIYKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQVDLKHLDQIPGSNLVQVGIDLTEFYLSVEWDILEVPATKNEEYYPDTLEPFSDITFKLTMRRKTLFYTVNLIVPCVALTFLTVLVFYLPSDSGEKVTLCISILVSLTVFFLLLAEIIPPTSLAVPLLGKYLLFTMILVSLSVWTTVCVLNIHFRSPSTHNMSPLVRKLFLHFMPKLMMMRRTQYTLPDYDDSTPSNGYTNEIDVRDSISDFPSEFKDSQDGAYDNGMQNSVDSDNVIPRNLTPEVLQALRAVRFIAQHIKDADKDNEIVEDWKFVSMVLDRFFLWLFTLSCVFGTLAIICQSPSLYDTRSPIDRQLSEIPLRKNNFMLPPDIVRQVLT
  
Inhibitor
Name:
BDBM50487981
Synonyms:
CHEMBL2269818
Type:
Small organic molecule
Emp. Form.:
C9H13ClN4O2S
Mol. Mass.:
276.743
SMILES:
CCN(Cc1cnc(Cl)s1)C(\NC)=C\[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: