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Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM50240347
Substrate
n/a
Meas. Tech.
ChEMBL_933250 (CHEMBL3069174)
IC50
6000±n/a nM
Citation
  TBA Med Chem Res 22:3126-3133 (2013)    Article 
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2
Type:
Nuclear Receptor
Mol. Mass.:
57613.46
Organism:
Homo sapiens (Human)
Description:
P37231
Residue:
505
Sequence:
MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM50240347
Synonyms:
(9,12,15)-linolenic acid | (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid | (Z,Z,Z)-9,12,15-octadecatrienoic acid | 9-cis,12-cis,15-cis-octadecatrienoic acid | ALA | CHEMBL8739 | all-cis-9,12,15-octadecatrienoic acid | alpha-linolenic acid | cid_5280934 | cis,cis,cis-9,12,15-octadecatrienoic acid | cis-Delta(9,12,15)-octadecatrienoic acid | linolenic acid
Type:
Small organic molecule
Emp. Form.:
C18H30O2
Mol. Mass.:
278.4296
SMILES:
CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O
Structure:
Search PDB for entries with ligand similarity: