Reaction Details Report a problem with these data
Target
Muscarinic receptor M1
Ligand
BDBM50034869
Substrate
n/a
Meas. Tech.
ChEMBL_138130 (CHEMBL872660)
Ki
17.9±n/a nM
Citation
 Kiesewetter, DO; Silverton, JV; Eckelman, WC Syntheses and biological properties of chiral fluoroalkyl quinuclidinyl benzilates. J Med Chem 38:1711-9 (1995) [PubMed]  Article 
Target
Name:
Muscarinic receptor M1
Synonyms:
Muscarinic acetylcholine receptor M1
Type:
PROTEIN
Mol. Mass.:
15022.43
Organism:
Bos taurus
Description:
ChEMBL_140161
Residue:
139
Sequence:
ETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRTPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPAKQPPRSSPNTVKRPTRKGRERAGKGQKPRGKEQLAKR
  
Inhibitor
Name:
BDBM50034869
Synonyms:
(R)-(4-Fluoromethyl-phenyl)-hydroxy-phenyl-acetic acid 1-aza-bicyclo[2.2.2]oct-3-yl ester | CHEMBL297276
Type:
Small organic molecule
Emp. Form.:
C22H24FNO3
Mol. Mass.:
369.4293
SMILES:
O[C@](C(=O)OC1CN2CCC1CC2)(c1ccccc1)c1ccc(CF)cc1 |wU:1.1,wD:1.0,THB:4:5:9.8:11.12,(7.07,-6.11,;6.32,-7.44,;7.84,-8,;8.09,-9.51,;9.02,-7.02,;10.47,-7.55,;11.24,-6.33,;12.94,-5.56,;14.5,-6.49,;13.7,-7.63,;12.1,-6.68,;12.1,-5.3,;12.94,-4.49,;5.53,-8.77,;6.27,-10.08,;5.5,-11.4,;3.96,-11.4,;3.19,-10.05,;3.99,-8.74,;4.98,-6.67,;3.64,-7.44,;2.32,-6.67,;2.32,-5.13,;.97,-4.36,;.97,-2.82,;3.64,-4.34,;4.98,-5.11,)|
Structure:
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