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Target
3',5'-cyclic-AMP phosphodiesterase
Ligand
BDBM50038975
Substrate
n/a
Meas. Tech.
ChEMBL_155848 (CHEMBL766944)
IC50
>100000±n/a nM
Citation
 Takase, Y; Saeki, T; Watanabe, N; Adachi, H; Souda, S; Saito, I Cyclic GMP phosphodiesterase inhibitors. 2. Requirement of 6-substitution of quinazoline derivatives for potent and selective inhibitory activity. J Med Chem 37:2106-11 (1994) [PubMed]  Article 
Target
Name:
3',5'-cyclic-AMP phosphodiesterase
Synonyms:
Phosphodiesterase 4A
Type:
PROTEIN
Mol. Mass.:
13615.65
Organism:
Sus scrofa
Description:
ChEMBL_155848
Residue:
118
Sequence:
PWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVDIPSPTMKDHEKQQAPRQRPSQQPPPPGPQFQPMSQITGVKKLMHSSSLNEDSSIPRFGVKTDQEELLAQEL
  
Inhibitor
Name:
BDBM50038975
Synonyms:
Benzo[1,3]dioxol-5-ylmethyl-(6-methylsulfanyl-quinazolin-4-yl)-amine | CHEMBL304927
Type:
Small organic molecule
Emp. Form.:
C17H15N3O2S
Mol. Mass.:
325.385
SMILES:
CSc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1
Structure:
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