Reaction Details Report a problem with these data
Target
Group 10 secretory phospholipase A2
Ligand
BDBM50004499
Substrate
n/a
Meas. Tech.
ChEMBL_156341 (CHEMBL759984)
IC50
30000±n/a nM
Citation
 Beaton, HG; Bennion, C; Connolly, S; Cook, AR; Gensmantel, NP; Hallam, C; Hardy, K; Hitchin, B; Jackson, CG; Robinson, DH Discovery of new non-phospholipid inhibitors of the secretory phospholipases A2. J Med Chem 37:557-9 (1994) [PubMed]  Article 
Target
Name:
Group 10 secretory phospholipase A2
Synonyms:
Group X secretory phospholipase A2 | PA2GX_HUMAN | PLA2G10
Type:
PROTEIN
Mol. Mass.:
18153.11
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1442449
Residue:
165
Sequence:
MGPLPVCLPIMLLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD
  
Inhibitor
Name:
BDBM50004499
Synonyms:
(R)-O-(2-Hexadecanamidoisohexyl) phosphocholine | CHEMBL322409 | {2-[(2-Hexadecanoyl amino-4-methyl-p entyloxy)-hydroxy-phoryloxy]-ethyl}-trimethyl-ammonium
Type:
Small organic molecule
Emp. Form.:
C27H57N2O5P
Mol. Mass.:
520.7256
SMILES:
CCCCCCCCCCCCCCCC(=O)N[C@@H](COP([O-])(=O)OCC[N+](C)(C)C)CC(C)C
Structure:
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