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TargetMatrix metalloproteinase-1 (MMP1)
LigandBDBM50043599
Substrate/Competitorn/a
Meas. Tech.ChEMBL_49504
IC50>60000±n/a nM
Citation Chapman, KTKopka, IEDurette, PLEsser, CKLanza, TJIzquierdo-Martin, MNiedzwiecki, LChang, BHarrison, RKKuo, DW Inhibition of matrix metalloproteinases by N-carboxyalkyl peptides. J Med Chem36:4293-301 (1994) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Matrix metalloproteinase-1 (MMP1)
Name:Matrix metalloproteinase (1 and 13)
Synonyms:Fibroblast collagenase | Interstitial collagenase | MMP1 | Matrix metalloproteinase-1 | Matrix metalloproteinase-1 (MMP-1)
Type:Enzyme
Mol. Mass.:54010.26
Organism:Homo sapiens (Human)
Description:
Residue:469
Sequence:
MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPV
VEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIEN
YTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGN
LAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSY
TFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDR
FYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGY
PKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFP
GIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
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  Blast E-value cutoff:
BDBM50043599
NameBDBM50043599
Synonyms:1N-[1-[1-carbamoyl-(1S)-pentylcarbamoyl]-3-methyl-(1S)-butyl]-2-[1-[1-amino-(1R)-ethylcarboxamido]-2-(1H-3-indolyl)-(1S)-ethylcarboxamido]-(2S)-hexanamide | CHEMBL265583
TypeSmall organic molecule
Emp. Form.C32H51N7O5
Mol. Mass.613.7912
SMILESCCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCC)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](C)N)C(N)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
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