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Target
Acyl-protein thioesterase 2
Ligand
BDBM207992
Substrate
n/a
Meas. Tech.
ChEMBL_1300900 (CHEMBL3135187)
Ki
230±n/a nM
Citation
 Davda, D; Martin, BR Acyl protein thioesterase inhibitors as probes of dynamic S-palmitoylation. Medchemcomm 5:268-276 (2014) [PubMed]  Article 
Target
Name:
Acyl-protein thioesterase 2
Synonyms:
APT2 | Acyl-protein thioesterase 2 (APT2 WT) | LYPA2_HUMAN | LYPLA2 | Lysophospholipase II
Type:
Protein
Mol. Mass.:
24740.23
Organism:
Homo sapiens (Human)
Description:
O95372
Residue:
231
Sequence:
MCGNTMSVPLLTDAATVSGAERETAAVIFLHGLGDTGHSWADALSTIRLPHVKYICPHAPRIPVTLNMKMVMPSWFDLMGLSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFPQAANGSAKDLAILQCHGELDPMVPVRFGALTAEKLRSVVTPARVQFKTYPGVMHSSCPQEMAAVKEFLEKLLPPV
  
Inhibitor
Name:
BDBM207992
Synonyms:
ML349
Type:
Small organic molecule
Emp. Form.:
C23H22N2O4S2
Mol. Mass.:
454.562
SMILES:
COc1ccc(cc1)N1CCN(CC1)C(=O)c1cc2CS(=O)(=O)c3ccccc3-c2s1
Structure:
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