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Target
D(1A) dopamine receptor
Ligand
BDBM86525
Substrate
n/a
Meas. Tech.
ChEBML_58991
Ki
2530±n/a nM
Citation
 Ismaiel, AM; De Los Angeles, J; Teitler, M; Ingher, S; Glennon, RA Antagonism of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane stimulus with a newly identified 5-HT2- versus 5-HT1C-selective antagonist. J Med Chem 36:2519-25 (1993) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
D(1A) dopamine receptor | DOPAMINE D1 | DRD1_MOUSE | Dopamine D1 receptor | Dopamine receptor | Drd1 | Drd1a | Gpcr15
Type:
Enzyme
Mol. Mass.:
49613.93
Organism:
Mus musculus (Mouse)
Description:
Q61616
Residue:
446
Sequence:
MAPNTSTMDETGLPVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDAEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPVECSQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVMFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKREEAGGIPKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM86525
Synonyms:
AMI-193 | CAS_77445 | CHEMBL79834 | NSC_77445
Type:
Small organic molecule
Emp. Form.:
C22H26FN3O2
Mol. Mass.:
383.4591
SMILES:
Fc1ccc(OCCCN2CCC3(CC2)N(CNC3=O)c2ccccc2)cc1
Structure:
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