Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50018171
Substrate
n/a
Meas. Tech.
ChEBML_29016
Ki
15000±n/a nM
Citation
 Jacobson, KA; Shi, D; Gallo-Rodriguez, C; Manning, M; Müller, C; Daly, JW; Neumeyer, JL; Kiriasis, L; Pfleiderer, W Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors. J Med Chem 36:2639-44 (1993) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50018171
Synonyms:
1,3,7-Trimethyl-8-phenyl-3,7-dihydro-purine-2,6-dione | 1,3,7-trimethyl-8-phenyl-3,4,5,7-tetrahydro-1H-purine-2,6-dione | CHEMBL21053
Type:
Small organic molecule
Emp. Form.:
C14H14N4O2
Mol. Mass.:
270.2866
SMILES:
Cn1c(nc2n(C)c(=O)n(C)c(=O)c12)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: